GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs7973719 | 1 | rs12828421 | chr12:7335217 | PEX5 | chr12:7341759-7371167:+ | -0.25 | -4.21 | 3.23E-5 | IgG glycosylation |
| BLCA | cis | rs11622475 | 1 | rs12886745 | chr14:104523839 | TDRD9 | chr14:104394817-104519002:+ | 0.32 | 4.82 | 2.1E-6 | Bipolar disorder |
| BLCA | cis | rs11622475 | 1 | rs12889168 | chr14:104481957 | TDRD9 | chr14:104394817-104519002:+ | 0.32 | 5.3 | 1.96E-7 | Bipolar disorder |
| BLCA | cis | rs2404602 | 1 | rs12898430 | chr15:76874923 | SCAPER | chr15:76640529-77197744:- | -0.21 | -4.57 | 6.55E-6 | Blood metabolite levels |
| BLCA | cis | rs12908161 | 1 | rs12899981 | chr15:85302373 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.16 | 3.87E-5 | Schizophrenia |
| BLCA | cis | rs950169 | 1 | rs12902672 | chr15:84716986 | LOC388152 | chr15:84867600-84898920:- | -0.26 | -4.55 | 7.19E-6 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs12903134 | chr15:85337699 | LOC388152 | chr15:84867600-84898920:- | -0.23 | -4.16 | 4.0E-5 | Schizophrenia |
| BLCA | cis | rs950169 | 1 | rs12903820 | chr15:84723820 | LOC388152 | chr15:84867600-84898920:- | -0.26 | -4.55 | 7.19E-6 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs12905057 | chr15:85210765 | LOC388152 | chr15:84867600-84898920:- | -0.25 | -4.25 | 2.73E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs12908161 | chr15:85207825 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.07 | 5.81E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs12908549 | chr15:85322351 | LOC388152 | chr15:84867600-84898920:- | -0.23 | -4.18 | 3.68E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs12910012 | chr15:85298662 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.15 | 4.1E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs12911736 | chr15:85240008 | LOC388152 | chr15:84867600-84898920:- | -0.25 | -4.27 | 2.47E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs12912388 | chr15:85344550 | LOC388152 | chr15:84867600-84898920:- | -0.23 | -4.16 | 4.0E-5 | Schizophrenia |
| BLCA | cis | rs4776059 | 1 | rs12914047 | chr15:52970993 | ARPP19 | chr15:52839432-52861364:- | 0.22 | 4 | 7.63E-5 | Schizophrenia |